alpha 2 Macroglobulin anticorps (N-Term)
Aperçu rapide pour alpha 2 Macroglobulin anticorps (N-Term) (ABIN2787981)
Antigène
Voir toutes alpha 2 Macroglobulin (A2M) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- PVPGHVTVSI CRKYSDASDC HGEDSQAFCE KFSGQLNSHG CFYQQVKTKV
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Homologie
- Human: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against A2M. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 1474 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
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Autre désignation
- A2M
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Sujet
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Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Alias Symbols: CPAMD5, DKFZp779B086, FWP007, S863-7, A2MD
Protein Interaction Partner: MAPK6, CDK7, CDK11A, HIPK1, FBXO6, CFTR, TP63, TGM2, IFIT3, DNAJB1, GCDH, FARSA, ENO2, ELAVL3, CYP2C18, CYP2C8, ATP1A1, APP, APOE, ACTB, A2M, RNF32, SWSAP1, TRAPPC5, EVI5L, EGLN2, IGSF8, PRAM1, MLST8, STAMBPL1, RETN, FBXL12, ECSIT, FIS1, EXOSC1, IFIT5, NC
Protein Size: 1474 -
Poids moléculaire
- 161 kDa
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ID gène
- 2
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NCBI Accession
- NM_000014, NP_000005
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UniProt
- P01023
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Pathways
- Lipid Metabolism
Antigène
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